Pub. Date : 2003 Feb 21
PMID : 12514169
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Host recognition of bacterial muramyl dipeptide mediated through NOD2. | muramyl | nucleotide binding oligomerization domain containing 2 | Homo sapiens |
| 2 | Host recognition of bacterial muramyl dipeptide mediated through NOD2. | Dipeptides | nucleotide binding oligomerization domain containing 2 | Homo sapiens |
| 3 | Biochemical and functional analyses identified muramyl dipeptide (MurNAc-L-Ala-D-isoGln) derived from peptidoglycan as the essential structure in bacteria recognized by NOD2. | Acetylmuramyl-Alanyl-Isoglutamine | nucleotide binding oligomerization domain containing 2 | Homo sapiens |
| 4 | Biochemical and functional analyses identified muramyl dipeptide (MurNAc-L-Ala-D-isoGln) derived from peptidoglycan as the essential structure in bacteria recognized by NOD2. | Acetylmuramyl-Alanyl-Isoglutamine | nucleotide binding oligomerization domain containing 2 | Homo sapiens |
| 5 | Replacement of L-Ala for D-Ala or D-isoGln for L-isoGln eliminated the ability of muramyl dipeptide to stimulate NOD2, indicating stereoselective recognition. | polyalanine | nucleotide binding oligomerization domain containing 2 | Homo sapiens |
| 6 | Replacement of L-Ala for D-Ala or D-isoGln for L-isoGln eliminated the ability of muramyl dipeptide to stimulate NOD2, indicating stereoselective recognition. | d-isogln | nucleotide binding oligomerization domain containing 2 | Homo sapiens |
| 7 | Replacement of L-Ala for D-Ala or D-isoGln for L-isoGln eliminated the ability of muramyl dipeptide to stimulate NOD2, indicating stereoselective recognition. | l-isogln | nucleotide binding oligomerization domain containing 2 | Homo sapiens |
| 8 | Replacement of L-Ala for D-Ala or D-isoGln for L-isoGln eliminated the ability of muramyl dipeptide to stimulate NOD2, indicating stereoselective recognition. | Dipeptides | nucleotide binding oligomerization domain containing 2 | Homo sapiens |
| 9 | Muramyl dipeptide was recognized by NOD2 but not by TLR2 or co-expression of TLR2 with TLR1 or TLR6. | Acetylmuramyl-Alanyl-Isoglutamine | nucleotide binding oligomerization domain containing 2 | Homo sapiens |
| 10 | NOD2 mutants associated with susceptibility to Crohn"s disease were deficient in their recognition of muramyl dipeptide. | Dipeptides | nucleotide binding oligomerization domain containing 2 | Homo sapiens |