Title : [The expression of bcl-2 and bax genes during microcystin induced liver tumorigenesis].

Pub. Date : 2002 Jul

PMID : 12411203






5 Functional Relationships(s)
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1 (2) MC decreased the expression of bax gene. microcystin BCL2 associated X, apoptosis regulator Rattus norvegicus
2 The intensity and area of bax gene expression in the pure MC toxin group were 0.028 3 AODV and 0.007 3 ( micro m(2)/ micro m(2)) and in the DEN control group were 0.065 5 AODV and 0.024 4 ( micro m(2)/ micro m(2)), respectively. microcystin BCL2 associated X, apoptosis regulator Rattus norvegicus
3 The intensity and areas of bax gene expression in the pure MC toxin group were significantly lower than those in the DEN control group (P < 0.05). microcystin BCL2 associated X, apoptosis regulator Rattus norvegicus
4 (3) MC increased the expression of bcl-2 gene. microcystin BCL2, apoptosis regulator Rattus norvegicus
5 The intensity and area of bcl-2 gene expression in the pure MC toxin group wee 0.097 7 AODV and 0.031 5 ( micro m(2)/ micro m(2)), respectively, and in the DEN control group were 0.046 0 AODV and 0.020 5 ( micro m(2)/ micro m(2)) respectively (P < 0.05). microcystin BCL2, apoptosis regulator Rattus norvegicus