Pub. Date : 2002 Feb
PMID : 11853173
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When determined at 2 mM substrate concentration, nonylphenol (1 mM) most efficiently inhibited aminopyrine N-demethylation by CYP2C9 and CYP2C19, by 61% and 59%, respectively, followed by CYP2D6, CYP1A2, CYP2C18 and CYP2C8 (46-51%), whereas inhibition of the activities by other CYPs was less than 27%. | nonylphenol | cytochrome P450 family 2 subfamily C member 18 | Homo sapiens |