Title : The use of a high-volume screening procedure to assess the effects of dietary flavonoids on human cyp1a1 expression.

Pub. Date : 2001 Aug

PMID : 11454723






2 Functional Relationships(s)
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1 Cotreatment of cells with TCDD and GTE, naringenin, and apigenin resulted in 58, 77, and 74% reductions, respectively, in TCDD-mediated CYP1A1 induction, indicating that these flavonoids exhibit potential antagonist activity toward the aryl hydrocarbon (Ah) receptor. naringenin cytochrome P450 family 1 subfamily A member 1 Homo sapiens
2 Cotreatment of cells with TCDD and GTE, naringenin, and apigenin resulted in 58, 77, and 74% reductions, respectively, in TCDD-mediated CYP1A1 induction, indicating that these flavonoids exhibit potential antagonist activity toward the aryl hydrocarbon (Ah) receptor. naringenin aryl hydrocarbon receptor Homo sapiens