Title : Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels.

Pub. Date : 2001 May 22

PMID : 11353868






2 Functional Relationships(s)
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1 The mutated GIRK1 and GIRK2 (GIRK1/2) channels containing the high-affinity phosphatidylinositol 4,5-bisphosphate (PIP(2)) domain from IRK1, on the other hand, showed dramatically less inhibition with bupivacaine. Phosphatidylinositol 4,5-Diphosphate potassium inwardly rectifying channel subfamily J member 3 Homo sapiens
2 The mutated GIRK1 and GIRK2 (GIRK1/2) channels containing the high-affinity phosphatidylinositol 4,5-bisphosphate (PIP(2)) domain from IRK1, on the other hand, showed dramatically less inhibition with bupivacaine. Bupivacaine potassium inwardly rectifying channel subfamily J member 3 Homo sapiens