PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11353868-3 2001 Here, we report that extracellular application of the membrane-permeant local anesthetic bupivacaine selectively inhibited G protein-gated inwardly rectifying K(+) channels (GIRK:Kir3) but not other families of inwardly rectifying K(+) channels (ROMK:Kir1 and IRK:Kir2). Bupivacaine 89-100 potassium inwardly rectifying channel subfamily J member 1 Homo sapiens 246-250 11353868-3 2001 Here, we report that extracellular application of the membrane-permeant local anesthetic bupivacaine selectively inhibited G protein-gated inwardly rectifying K(+) channels (GIRK:Kir3) but not other families of inwardly rectifying K(+) channels (ROMK:Kir1 and IRK:Kir2). Bupivacaine 89-100 potassium inwardly rectifying channel subfamily J member 12 Homo sapiens 175-178 11353868-6 2001 The mutated GIRK1 and GIRK2 (GIRK1/2) channels containing the high-affinity phosphatidylinositol 4,5-bisphosphate (PIP(2)) domain from IRK1, on the other hand, showed dramatically less inhibition with bupivacaine. Phosphatidylinositol 4,5-Diphosphate 76-113 potassium inwardly rectifying channel subfamily J member 3 Homo sapiens 12-17 11353868-6 2001 The mutated GIRK1 and GIRK2 (GIRK1/2) channels containing the high-affinity phosphatidylinositol 4,5-bisphosphate (PIP(2)) domain from IRK1, on the other hand, showed dramatically less inhibition with bupivacaine. Phosphatidylinositol 4,5-Diphosphate 76-113 potassium inwardly rectifying channel subfamily J member 6 Homo sapiens 22-27 11353868-6 2001 The mutated GIRK1 and GIRK2 (GIRK1/2) channels containing the high-affinity phosphatidylinositol 4,5-bisphosphate (PIP(2)) domain from IRK1, on the other hand, showed dramatically less inhibition with bupivacaine. Phosphatidylinositol 4,5-Diphosphate 76-113 potassium inwardly rectifying channel subfamily J member 6 Homo sapiens 29-36 11353868-6 2001 The mutated GIRK1 and GIRK2 (GIRK1/2) channels containing the high-affinity phosphatidylinositol 4,5-bisphosphate (PIP(2)) domain from IRK1, on the other hand, showed dramatically less inhibition with bupivacaine. Phosphatidylinositol 4,5-Diphosphate 76-113 potassium inwardly rectifying channel subfamily J member 2 Homo sapiens 13-17 11353868-6 2001 The mutated GIRK1 and GIRK2 (GIRK1/2) channels containing the high-affinity phosphatidylinositol 4,5-bisphosphate (PIP(2)) domain from IRK1, on the other hand, showed dramatically less inhibition with bupivacaine. Bupivacaine 201-212 potassium inwardly rectifying channel subfamily J member 3 Homo sapiens 12-17 11353868-6 2001 The mutated GIRK1 and GIRK2 (GIRK1/2) channels containing the high-affinity phosphatidylinositol 4,5-bisphosphate (PIP(2)) domain from IRK1, on the other hand, showed dramatically less inhibition with bupivacaine. Bupivacaine 201-212 potassium inwardly rectifying channel subfamily J member 6 Homo sapiens 22-27 11353868-6 2001 The mutated GIRK1 and GIRK2 (GIRK1/2) channels containing the high-affinity phosphatidylinositol 4,5-bisphosphate (PIP(2)) domain from IRK1, on the other hand, showed dramatically less inhibition with bupivacaine. Bupivacaine 201-212 potassium inwardly rectifying channel subfamily J member 6 Homo sapiens 29-36 11353868-7 2001 Surprisingly, GIRK1/2 channels with high affinity for PIP(2) were inhibited by ethanol, like IRK1 channels. Phosphatidylinositol 4,5-Diphosphate 54-60 potassium inwardly rectifying channel subfamily J member 6 Homo sapiens 14-21 11353868-7 2001 Surprisingly, GIRK1/2 channels with high affinity for PIP(2) were inhibited by ethanol, like IRK1 channels. Phosphatidylinositol 4,5-Diphosphate 54-60 potassium inwardly rectifying channel subfamily J member 2 Homo sapiens 15-19 11353868-7 2001 Surprisingly, GIRK1/2 channels with high affinity for PIP(2) were inhibited by ethanol, like IRK1 channels. Ethanol 79-86 potassium inwardly rectifying channel subfamily J member 6 Homo sapiens 14-21 11353868-7 2001 Surprisingly, GIRK1/2 channels with high affinity for PIP(2) were inhibited by ethanol, like IRK1 channels. Ethanol 79-86 potassium inwardly rectifying channel subfamily J member 2 Homo sapiens 15-19