Title : Induction of P-glycoprotein and cytochrome P450 3A by HIV protease inhibitors.

Pub. Date : 2001 May

PMID : 11302944






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Nelfinavir treatment increased expression of intestinal Pgp and hepatic CYP3A levels by 83 and 85%, respectively, but not hepatic Pgp or intestinal CYP3A. Nelfinavir ATP binding cassette subfamily B member 1 Homo sapiens
2 Nelfinavir treatment increased expression of intestinal Pgp and hepatic CYP3A levels by 83 and 85%, respectively, but not hepatic Pgp or intestinal CYP3A. Nelfinavir cytochrome P450 family 3 subfamily A member 4 Homo sapiens