Title : Glucuronidation of catechol estrogens by expressed human UDP-glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7.

Pub. Date : 1998 Sep

PMID : 9848110






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Flunitrazepam (FNZ), a competitive inhibitor of morphine glucuronidation in hepatic microsomes, competitively inhibited catechol estrogen glucuronidation catalyzed by UGT2B7(Y), UGT1A1, and UGT1A3. Flunitrazepam UDP glucuronosyltransferase family 2 member B7 Homo sapiens