Protein Name | UDP glucuronosyltransferase family 2 member B7 |
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Organism | Homo sapiens |
Gene ID | 7364 |
Gene Symbol | UGT2B7 |
UniProt | P16662 (UD2B7_HUMAN), E9PBP8 (E9PBP8_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
482
Total Number of Articles : 465 |
Description |
UDP glucuronosyltransferase family 2 member B7 |
Gene Summary |
The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017] |
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Properties | |