Protein Name UDP glucuronosyltransferase family 2 member B7
Organism Homo sapiens
Gene ID 7364
Gene Symbol

UGT2B7

UniProt P16662 (UD2B7_HUMAN), E9PBP8 (E9PBP8_HUMAN)
Relationships Total Number of functionally related compound(s) : 482
Total Number of Articles : 465
Description

UDP glucuronosyltransferase family 2 member B7

Gene Summary

The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017]

synonyms
  • UDP-glucuronosyltransferase 2B7
  • 3,4-catechol estrogen specific
  • 3,4-catechol estrogen-specific UDPGT
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Properties