Title : Lipoprotein lipase expression exclusively in liver. A mouse model for metabolism in the neonatal period and during cachexia.

Pub. Date : 1998 Sep 1

PMID : 9727057






2 Functional Relationships(s)
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1 Adult mice expressing LPL exclusively in liver had slower VLDL turnover than wild-type mice, but greater VLDL mass clearance, increased VLDL triglyceride production, and three- to fourfold more plasma ketones. Triglycerides lipoprotein lipase Mus musculus
2 In summary, it appears that liver LPL shunts circulating triglycerides to the liver, which results in a futile cycle of enhanced VLDL production and increased ketone production, and subsequently spares glucose. Triglycerides lipoprotein lipase Mus musculus