Protein Name lipoprotein lipase
Organism Mus musculus
Gene ID 16956
Gene Symbol

Lpl

UniProt P11152 (LIPL_MOUSE)
Relationships Total Number of functionally related compound(s) : 321
Total Number of Articles : 493
Description

lipoprotein lipase

Gene Summary

Enables lipoprotein lipase activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of macrophage derived foam cell differentiation; and triglyceride catabolic process. Acts upstream of or within response to bacterium. Located in cell surface and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; limb; lung; and sensory organ. Used to study familial lipoprotein lipase deficiency. Human ortholog(s) of this gene implicated in Alzheimer's disease; artery disease (multiple); familial hyperlipidemia (multiple); muscular disease; and type 2 diabetes mellitus. Orthologous to human LPL (lipoprotein lipase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • lipoprotein lipase
  • O 1-4-5
  • phospholipase A1
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Properties