Title : Related adhesion focal tyrosine kinase and the epidermal growth factor receptor mediate the stimulation of mitogen-activated protein kinase by the G-protein-coupled P2Y2 receptor. Phorbol ester or [Ca2+]i elevation can substitute for receptor activation.

Pub. Date : 1998 Sep 4

PMID : 9722539






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 AG1478, a tyrphostin selective for the EGF receptor, reduced the activation of MAP kinase, the tyrosine phosphorylation of SHC, the association of Grb2 with SHC, and the tyrosine phosphorylation of the EGF receptor and p120(cbl) but did not block the tyrosine phosphorylation of RAFTK. Tyrphostins epidermal growth factor receptor Rattus norvegicus