Title : Regulation of the growth hormone-insulin-like growth factor I axis in developing and adult monkeys is affected by estradiol replacement and supplementation with insulin-like growth factor I.

Pub. Date : 1998 Jun

PMID : 9626134






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Estradiol replacement significantly increased both serum IGF-I and IGFBP-3 through adolescence, even in IGF-I-supplemented animals. Estradiol insulin like growth factor binding protein 3 Homo sapiens
2 However, with the transition from adolescence, estradiol suppressed serum IGF-I secretion, yet continued to increase IGFBP-3 in young adult and fully adult females. Estradiol insulin like growth factor binding protein 3 Homo sapiens