Protein Name insulin like growth factor binding protein 3
Organism Homo sapiens
Gene ID 3486
Gene Symbol


UniProt P17936 (IBP3_HUMAN), B3KPF0 (B3KPF0_HUMAN)
Relationships Total Number of functionally related compound(s) : 446
Total Number of Articles : 837

insulin like growth factor binding protein 3

Gene Summary

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

  • insulin-like growth factor-binding protein 3
  • IGF-binding protein 3
  • acid stable subunit of the 140 K IGF complex
Click to show/hide the synonyms