Title : Charge distribution of flanking amino acids inhibits O-glycosylation of several single-site acceptors in vivo.

Pub. Date : 1997 Dec

PMID : 9455905






1 Functional Relationships(s)
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1 Previously, we demonstrated that the in vivo O-glycosylation of a sequence derived from a known glycosylation site of human von Willebrand factor (PHMAQVTVGPGL) was markedly reduced when charged residues were substituted at position -1 and +3 relative to the single threonine. Threonine von Willebrand factor Homo sapiens