Protein Name von Willebrand factor
Organism Homo sapiens
Gene ID 7450
Gene Symbol


UniProt P04275 (VWF_HUMAN)
Relationships Total Number of functionally related compound(s) : 850
Total Number of Articles : 1972

von Willebrand factor

Gene Summary

This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]

  • von Willebrand factor
  • Factor VIII related antigen
  • coagulation factor VIII VWF
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