Title : Stereochemistry of oxygenation of linoleic acid catalyzed by prostaglandin-endoperoxide H synthase-2.

Pub. Date : 1998 Jan 15

PMID : 9448728






3 Functional Relationships(s)
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1 As a comparison, linoleic acid was incubated with microsomal prostaglandin-endoperoxide H synthase-1 (PGHS-1) from ovine vesicular gland. Linoleic Acid prostaglandin-endoperoxide synthase 1 Homo sapiens
2 As a comparison, linoleic acid was incubated with microsomal prostaglandin-endoperoxide H synthase-1 (PGHS-1) from ovine vesicular gland. Linoleic Acid prostaglandin-endoperoxide synthase 1 Homo sapiens
3 The stereochemistry of the hydrogen which was removed from C-11 during the conversion of linoleic acid into hydroxy acids in the presence of PGHS-1 or PGHS-2 was determined by incubation of [(11R)-2H]- and [(11S)-2H]linoleic acids followed by mass spectrometric analysis of the isotope contents of the individual hydroxy acid isomers. Linoleic Acid prostaglandin-endoperoxide synthase 1 Homo sapiens