Pub. Date : 1997 Nov 11
PMID : 9356453
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cholesterol also appeared to reduce the proteolytic processing of SREBP-2. | Cholesterol | sterol regulatory element binding transcription factor 2 | Homo sapiens |
| 2 | In addition, at high levels of dietary cholesterol the mRNA encoding SREBP-2 declined and the amount of the precursor also fell, suggesting that cholesterol accumulation also may inhibit transcription of the SREBP-2 gene. | Cholesterol | sterol regulatory element binding transcription factor 2 | Homo sapiens |
| 3 | In addition, at high levels of dietary cholesterol the mRNA encoding SREBP-2 declined and the amount of the precursor also fell, suggesting that cholesterol accumulation also may inhibit transcription of the SREBP-2 gene. | Cholesterol | sterol regulatory element binding transcription factor 2 | Homo sapiens |
| 4 | In addition, at high levels of dietary cholesterol the mRNA encoding SREBP-2 declined and the amount of the precursor also fell, suggesting that cholesterol accumulation also may inhibit transcription of the SREBP-2 gene. | Cholesterol | sterol regulatory element binding transcription factor 2 | Homo sapiens |
| 5 | In addition, at high levels of dietary cholesterol the mRNA encoding SREBP-2 declined and the amount of the precursor also fell, suggesting that cholesterol accumulation also may inhibit transcription of the SREBP-2 gene. | Cholesterol | sterol regulatory element binding transcription factor 2 | Homo sapiens |
| 6 | Treatment with lovastatin and Colestipol, which increases hepatic demands for cholesterol, increased the amount of SREBP-2 mRNA as well as the precursor and nuclear forms of the protein. | Cholesterol | sterol regulatory element binding transcription factor 2 | Homo sapiens |