Title : A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression.

Pub. Date : 1997 Oct 6

PMID : 9314533






2 Functional Relationships(s)
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1 However, transfection with MKK6 (Glu), which specifically activated p38, augmented cell size, induced NP and alpha-Ska promoter activities by up to 130-fold, and elicited sarcomeric organization in a manner similar to PE. Glutamic Acid mitogen-activated protein kinase 1 Homo sapiens
2 Moreover, all three growth features induced by MKK6 (Glu) or PE were blocked with the p38-specific inhibitor, SB 203580. Glutamic Acid mitogen-activated protein kinase 1 Homo sapiens