Title : [Low extracellular pH has a role in the induction of NO synthase type 2 in macrophages].

Pub. Date : 1997 Feb

PMID : 9235225






2 Functional Relationships(s)
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1 Indeed, [1] elevated TNF-alpha bioactivity was observed in the medium of macrophages exposed to pH 7.0, and [2] incubation of macrophages with a neutralizing anti-TNF-alpha antibody impaired both NF-kappa B activation and nitrite accumulation in response to acid challenge. Nitrites tumor necrosis factor Rattus norvegicus
2 Indeed, [1] elevated TNF-alpha bioactivity was observed in the medium of macrophages exposed to pH 7.0, and [2] incubation of macrophages with a neutralizing anti-TNF-alpha antibody impaired both NF-kappa B activation and nitrite accumulation in response to acid challenge. Nitrites tumor necrosis factor Rattus norvegicus