Title : Pretreatment of human platelets with plasmin inhibits responses to thrombin, but potentiates responses to low concentrations of aggregating agents, including the thrombin receptor activating peptide, SFLLRN.

Pub. Date : 1997 Apr

PMID : 9134653






1 Functional Relationships(s)
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1 Incubation with 0.2 CU/ml of plasmin almost completely inhibited thrombin-induced (0.1 U/ml) aggregation, release of 14C-serotonin, and increase in cytosolic [Ca2+]. Carbon-14 coagulation factor II, thrombin Homo sapiens