Title : Identification of Shc docking site on Ret tyrosine kinase.

Pub. Date : 1997 Feb 20

PMID : 9047384






3 Functional Relationships(s)
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1 Moreover, our analysis has identified the Ret tyrosine residue and the Shc domains involved in the interaction. Tyrosine ret proto-oncogene Homo sapiens
2 In keeping with this finding, by using RET/PTC2-Y586F mutant, we have demonstrated that this tyrosine residue, the last amino acid but one before the divergence of the two Ret isoforms, is the docking site for Shc. Tyrosine ret proto-oncogene Homo sapiens
3 In keeping with this finding, by using RET/PTC2-Y586F mutant, we have demonstrated that this tyrosine residue, the last amino acid but one before the divergence of the two Ret isoforms, is the docking site for Shc. Tyrosine ret proto-oncogene Homo sapiens