Title : Mutation in the ligand-binding domain of the retinoic acid receptor alpha in HL-60 leukemic cells resistant to retinoic acid and with increased sensitivity to vitamin D3 analogs.

Pub. Date : 1996 Sep

PMID : 8947586






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mutation in the ligand-binding domain of the retinoic acid receptor alpha in HL-60 leukemic cells resistant to retinoic acid and with increased sensitivity to vitamin D3 analogs. Cholecalciferol retinoic acid receptor alpha Homo sapiens
2 This mutation in the retinoic acid receptor alpha of the HL-60/RA cells may be responsible for drug resistance to ATRA and 9-cis-retinoic acid and increased sensitivity to vitamin D3 analogs. Cholecalciferol retinoic acid receptor alpha Homo sapiens