Protein Name retinoic acid receptor alpha
Organism Homo sapiens
Gene ID 5914
Gene Symbol

RARA

UniProt P10276 (RARA_HUMAN), F1D8N9 (F1D8N9_HUMAN), Q6I9R7 (Q6I9R7_HUMAN), A8MUP8 (A8MUP8_HUMAN), A8K840 (A8K840_HUMAN)
Relationships Total Number of functionally related compound(s) : 433
Total Number of Articles : 1345
Description

retinoic acid receptor alpha

Gene Summary

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]

synonyms
  • retinoic acid receptor alpha
  • PML-DDX5-RARA fusion
  • PML-DDX5-RARA fusion protein
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Properties