Title : Enzymology of mammalian phospholipases D: in vitro studies.

Pub. Date : 1996 May 24

PMID : 8681428






1 Functional Relationships(s)
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1 This review summarizes the in vitro evidence showing differential subcellular localization and chromatographic properties of putative PLD isozymes, their phospholipid and alcohol substrate specificities, their modulation by various divalent cations, small G proteins and protein kinase c isozymes, and the role of phosphatidylinositol 4,5-bisphosphate as a cofactor of phospholipase D. Alcohols glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens