Protein Name glycosylphosphatidylinositol specific phospholipase D1
Organism Homo sapiens
Gene ID 2822
Gene Symbol


UniProt P80108 (PHLD_HUMAN)
Relationships Total Number of functionally related compound(s) : 761
Total Number of Articles : 1013

glycosylphosphatidylinositol specific phospholipase D1

Gene Summary

Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008]

  • phosphatidylinositol-glycan-specific phospholipase D
  • GPI-specific phospholipase D
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