Title : Metabolism of des(64,65)-human proinsulin in the rat. Evidence for the proteolytic processing to insulin.

Pub. Date : 1993 Oct

PMID : 8375581






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The data indicate proteolytic processing of des(64,65)-human proinsulin involves an initial tryptic cleavage at the carboxy side of ArgB32, with the formation of human insulin by the subsequent action of a carboxypeptidase to remove the ArgB31-ArgB32 dipeptide from diarginyl(B31,32)-human insulin. Dipeptides insulin Homo sapiens
2 The data indicate proteolytic processing of des(64,65)-human proinsulin involves an initial tryptic cleavage at the carboxy side of ArgB32, with the formation of human insulin by the subsequent action of a carboxypeptidase to remove the ArgB31-ArgB32 dipeptide from diarginyl(B31,32)-human insulin. Dipeptides insulin Homo sapiens