Title : Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies.

Pub. Date : 1993 Aug 18

PMID : 8340945






2 Functional Relationships(s)
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1 PURPOSE: Our purpose was to study, in vitro and in vivo, the antitumor effects of doxorubicin in combination with anti-EGF receptor MAbs against tumor cells expressing high levels of EGF receptor. Doxorubicin epidermal growth factor receptor Homo sapiens
2 CONCLUSIONS: Our results suggest that anti-EGF receptor MAbs substantially enhance the effects of doxorubicin against well-established xenografts of tumor cells expressing high levels of EGF receptors. Doxorubicin epidermal growth factor receptor Homo sapiens