Title : Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily.

Pub. Date : 1994 Apr 29

PMID : 8185679






1 Functional Relationships(s)
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1 In conclusion, CYP3A4, CYP3A5, and fetal microsomes containing CYP3A7 catalyze 1"- and 4-hydroxylation of midazolam with the ratio of these metabolites indicative of the CYP3A form. Midazolam cytochrome P450 family 3 subfamily A member 5 Homo sapiens