Pub. Date : 1994 Sep 9
PMID : 8077192
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | cGMP-binding cGMP-specific phosphodiesterase (cG-BPDE) binds tightly to a Zn(2+)-chelate column (Francis, S. H., and Corbin, J. D. (1988) Methods Enzymol. | Zinc | phosphodiesterase 5A | Homo sapiens |
| 2 | cGMP-binding cGMP-specific phosphodiesterase (cG-BPDE) binds tightly to a Zn(2+)-chelate column (Francis, S. H., and Corbin, J. D. (1988) Methods Enzymol. | Zinc | phosphodiesterase 5A | Homo sapiens |
| 3 | Using three different approaches, Zn2+ is now shown to bind to cG-BPDE, and the Kd is determined to be approximately 0.5 microM, with a binding stoichiometry of approximately 3 mol of Zn2+/mol of monomer. | Zinc | phosphodiesterase 5A | Homo sapiens |
| 4 | Using three different approaches, Zn2+ is now shown to bind to cG-BPDE, and the Kd is determined to be approximately 0.5 microM, with a binding stoichiometry of approximately 3 mol of Zn2+/mol of monomer. | Zinc | phosphodiesterase 5A | Homo sapiens |
| 5 | The Zn2+ binding to cG-BPDE is not diminished by, nor is catalysis supported by, relatively high concentrations of Cu2+, Cd2+, Ca2+, or Fe2+. | Zinc | phosphodiesterase 5A | Homo sapiens |