Pub. Date : 1994 Nov
PMID : 7977706
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Kinetics of prostacyclin synthesis in PGHS-1-overexpressed endothelial cells. | Epoprostenol | prostaglandin-endoperoxide synthase 1 | Homo sapiens |
| 2 | The availability of a human endothelial cell overexpressed with prostaglandin H synthase-1 (PGHS-1) by retrovirus-mediated gene transfer made it possible to quantify the kinetics of prostacyclin [prostaglandin (PG)I2] synthesis and PGHS-1 turnover. | Epoprostenol | prostaglandin-endoperoxide synthase 1 | Homo sapiens |
| 3 | The availability of a human endothelial cell overexpressed with prostaglandin H synthase-1 (PGHS-1) by retrovirus-mediated gene transfer made it possible to quantify the kinetics of prostacyclin [prostaglandin (PG)I2] synthesis and PGHS-1 turnover. | Epoprostenol | prostaglandin-endoperoxide synthase 1 | Homo sapiens |
| 4 | The availability of a human endothelial cell overexpressed with prostaglandin H synthase-1 (PGHS-1) by retrovirus-mediated gene transfer made it possible to quantify the kinetics of prostacyclin [prostaglandin (PG)I2] synthesis and PGHS-1 turnover. | Epoprostenol | prostaglandin-endoperoxide synthase 1 | Homo sapiens |
| 5 | The availability of a human endothelial cell overexpressed with prostaglandin H synthase-1 (PGHS-1) by retrovirus-mediated gene transfer made it possible to quantify the kinetics of prostacyclin [prostaglandin (PG)I2] synthesis and PGHS-1 turnover. | Epoprostenol | prostaglandin-endoperoxide synthase 1 | Homo sapiens |
| 6 | The decline of PGI2 synthesis corresponded to the reduction of PGHS-1 mass. | Epoprostenol | prostaglandin-endoperoxide synthase 1 | Homo sapiens |
| 7 | These findings indicate that approximately 30% of PGHS-1 was degraded during each catalysis-induced autoinactivation and that the extent and duration of PGI2 synthesis are governed by the level of PGHS-1 mass. | Epoprostenol | prostaglandin-endoperoxide synthase 1 | Homo sapiens |