Pub. Date : 1993 Nov 5
PMID : 7901211
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine, a major component of tobacco smoke, stimulates catecholamine secretion and activates catecholamine biosynthetic enzymes such as tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) in adrenal medullary cells. | Nicotine | dopamine beta-hydroxylase | Rattus norvegicus |
| 2 | We investigated the effect of long term treatment with nicotine on TH and DBH gene expression in rat PC12 pheochromocytoma cells. | Nicotine | dopamine beta-hydroxylase | Rattus norvegicus |
| 3 | Nicotine treatment for 1-2 days increased both the TH and DBH mRNA levels. | Nicotine | dopamine beta-hydroxylase | Rattus norvegicus |