| Protein Name | dopamine beta-hydroxylase |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25699 |
| Gene Symbol | Dbh |
| UniProt | Q05754 (DOPO_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
253
Total Number of Articles : 478 |
Description |
dopamine beta-hydroxylase |
| Gene Summary |
Enables copper ion binding activity and dopamine beta-monooxygenase activity. Involved in several processes, including cellular response to manganese ion; cellular response to nicotine; and norepinephrine biosynthetic process. Located in several cellular components, including axon; dendrite; and neuronal cell body. Biomarker of brain ischemia; depressive disorder; hypertension; and portal hypertension. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; attention deficit hyperactivity disorder; dopamine beta-hydroxylase deficiency; hypertension; and migraine with aura. Orthologous to human DBH (dopamine beta-hydroxylase). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |