Protein Name dopamine beta-hydroxylase
Organism Rattus norvegicus
Gene ID 25699
Gene Symbol

Dbh

UniProt Q05754 (DOPO_RAT)
Relationships Total Number of functionally related compound(s) : 253
Total Number of Articles : 478
Description

dopamine beta-hydroxylase

Gene Summary

Enables copper ion binding activity and dopamine beta-monooxygenase activity. Involved in several processes, including cellular biogenic amine metabolic process; cellular response to manganese ion; and cellular response to nicotine. Located in several cellular components, including axon; dendrite; and neuronal cell body. Biomarker of brain ischemia; hypertension; mental depression; and portal hypertension. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; attention deficit hyperactivity disorder; dopamine beta-hydroxylase deficiency; hypertension; and migraine with aura. Orthologous to human DBH (dopamine beta-hydroxylase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • dopamine beta-hydroxylase
  • Dopamine beta hydroxylase (dopamine beta-monooxygenase)
  • dopamine beta-monooxygenase
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Properties