Pub. Date : 1995 May
PMID : 7572198
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It has previously been shown that caffeine, in a dose-dependent manner, increases the expression of the protooncogene c-fos in the rat brain, predominantly in the caudate-putamen and tuberculum olfactorium. | Caffeine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 2 | Thus, c-fos is induced in rat striatum following administration of caffeine and other xanthines that (provided they enter the brain) block adenosine receptors, suggesting an involvement of central adenosine receptors. | Caffeine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |