Title : In vivo and in vitro serine/threonine phosphorylations of epidermal growth factor receptor upon entry into the cell cycle.

Pub. Date : 1995 Jan

PMID : 7536439






3 Functional Relationships(s)
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1 In vivo and in vitro serine/threonine phosphorylations of epidermal growth factor receptor upon entry into the cell cycle. Serine epidermal growth factor receptor Homo sapiens
2 The epidermal growth factor receptor is phosphorylated primarily on serine and threonine, but not on tyrosine residues, in an S phase-dependent fashion, as determined by phosphoamino acid analysis and anti-phosphotyrosine immunoblotting. Serine epidermal growth factor receptor Homo sapiens
3 Although the mechanism for this ligand-independent phosphorylation is not known, its correlation with emergence from quiescence and entry into the cell cycle suggests that the phosphorylation of epidermal growth factor receptor on serine and threonine residues may have heretofore unknown role(s) in cell cycle entry and progression. Serine epidermal growth factor receptor Homo sapiens