Title : Galactitol accumulation by glucose-6-phosphate deficient fibroblasts: a cellular model for resistance to the complications of diabetes mellitus.

Pub. Date : 1983 Sep 26

PMID : 6412013






1 Functional Relationships(s)
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1 Sorbitol does not accumulate either in control or in G6PD deficient fibroblasts incubated in high glucose medium, most likely because of the action of sorbitol dehydrogenase, and the presence of a carrier-mediated glucose transport system in the cell membrane which limits the concentration of glucose that can accumulate in these cells. Sorbitol sorbitol dehydrogenase Homo sapiens