Title : Serotonergic conversion of MPTP and dopaminergic accumulation of MPP+.

Pub. Date : 1985 Sep 23

PMID : 3876242






1 Functional Relationships(s)
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1 These results support the concept that MPTP accumulates in serotonergic neurons where it is oxidized by monoamine oxidase B to MPP+, which is released and then is selectively accumulated in dopaminergic neurons via the dopamine uptake system. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine monoamine oxidase B Rattus norvegicus