Protein Name monoamine oxidase B
Organism Rattus norvegicus
Gene ID 25750
Gene Symbol

Maob

UniProt P19643 (AOFB_RAT)
Relationships Total Number of functionally related compound(s) : 456
Total Number of Articles : 623
Description

monoamine oxidase B

Gene Summary

Enables flavin adenine dinucleotide binding activity; identical protein binding activity; and primary amine oxidase activity. Involved in several processes, including negative regulation of serotonin secretion; positive regulation of dopamine metabolic process; and response to corticosterone. Located in mitochondrial outer membrane. Biomarker of Parkinson's disease and cholestasis. Human ortholog(s) of this gene implicated in Alzheimer's disease and Parkinson's disease. Orthologous to human MAOB (monoamine oxidase B). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • amine oxidase [flavin-containing] B
  • MAO-B
  • monoamine oxidase type B
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Properties