Pub. Date : 2022 May 16
PMID : 35592896
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effect of metformin on vitamin B12 levels in pediatric patients. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
| 2 | In adults, one well-documented side effect of metformin is vitamin B12 deficiency. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
| 3 | This study examined the changes of vitamin B12 levels in pediatric patients being treated with metformin administration. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
| 4 | The effects of varying doses of metformin on the mean vitamin B12 level were investigated at 6-month, 12-month, 24-month and 36-month intervals. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
| 5 | The degree of compliance of metformin intake on vitamin B12 level also was studied. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
| 6 | Mean vitamin B12 drop was only noticeable (p<0.05) in patients taking high dose of metformin with a good compliance. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
| 7 | Our findings suggest metformin treatment in children does not cause vitamin B12 deficiency; however, long-term treatment could reduce vitamin B12 levels when patients take a high dose consistently. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |