PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35592896-0	2022	The effect of metformin on vitamin B12 levels in pediatric patients.	Metformin	14-23	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	35-38	
35592896-2	2022	In adults, one well-documented side effect of metformin is vitamin B12 deficiency.	Metformin	46-55	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	67-70	
35592896-4	2022	This study examined the changes of vitamin B12 levels in pediatric patients being treated with metformin administration.	Metformin	95-104	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	43-46	
35592896-6	2022	The effects of varying doses of metformin on the mean vitamin B12 level were investigated at 6-month, 12-month, 24-month and 36-month intervals.	Metformin	32-41	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	62-65	
35592896-7	2022	The degree of compliance of metformin intake on vitamin B12 level also was studied.	Metformin	28-37	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	56-59	
35592896-9	2022	Mean vitamin B12 drop was only noticeable (p<0.05) in patients taking high dose of metformin with a good compliance.	Metformin	83-92	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	13-16	
35592896-13	2022	Our findings suggest metformin treatment in children does not cause vitamin B12 deficiency; however, long-term treatment could reduce vitamin B12 levels when patients take a high dose consistently.	Metformin	21-30	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	142-145