Title : miRNA-34c-5p targets Fra-1 to inhibit pulmonary fibrosis induced by silica through p53 and PTEN/PI3K/Akt signaling pathway.

Pub. Date : 2022 May 2

PMID : 35499148






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 miRNA-34c-5p targets Fra-1 to inhibit pulmonary fibrosis induced by silica through p53 and PTEN/PI3K/Akt signaling pathway. Silicon Dioxide phosphatase and tensin homolog Homo sapiens
2 In addition, through interaction with PTEN/p53 it inhibits the proliferation and migration of human bronchial epithelial cells stimulated by silica, and promotes cell apoptosis, thereby preventing EMT. Silicon Dioxide phosphatase and tensin homolog Homo sapiens