Title : The protective effects of butorphanol tartrate against homocysteine-induced blood-brain barrier dysfunction.

Pub. Date : 2022 Mar

PMID : 35245993






2 Functional Relationships(s)
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1 We found that the increased diffusion of sodium fluorescein and Evan"s blue, declined expression of Claudin-5, and increased production of interleukin- 6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) were observed in Hcy-treated mice, which were all significantly reversed by butorphanol tartrate. Homocysteine interleukin 6 Mus musculus
2 We found that the increased diffusion of sodium fluorescein and Evan"s blue, declined expression of Claudin-5, and increased production of interleukin- 6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) were observed in Hcy-treated mice, which were all significantly reversed by butorphanol tartrate. Homocysteine interleukin 6 Mus musculus