Pub. Date : 2022
PMID : 35154461
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Targeted inhibition of ACLY expression to reverse the resistance of sorafenib in hepatocellular carcinoma. | Sorafenib | ATP citrate lyase | Homo sapiens |
| 2 | ACLY expression was higher in sorafenib-resistant cells and HCC-cell sensitivity to sorafenib increased after ACLY-knockout. | Sorafenib | ATP citrate lyase | Homo sapiens |
| 3 | ACLY expression was higher in sorafenib-resistant cells and HCC-cell sensitivity to sorafenib increased after ACLY-knockout. | Sorafenib | ATP citrate lyase | Homo sapiens |
| 4 | These data suggest that ACLY downregulation can reverse sorafenib resistance, and that SS-PEI can be used to mediate shRNA-ACLY transfection in HCC treatment. | Sorafenib | ATP citrate lyase | Homo sapiens |