Pub. Date : 2022 Mar 30
PMID : 35124147
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sorafenib is an antagonist of the aryl hydrocarbon receptor. | Sorafenib | aryl hydrocarbon receptor | Homo sapiens |
| 2 | Sorafenib"s antagonistic action on AhR was comparable to that of the known AhR antagonist CH-223191 in human liver and ovarian cell lines. | Sorafenib | aryl hydrocarbon receptor | Homo sapiens |
| 3 | In summary, we demonstrate that sorafenib is a potent AhR antagonist and likely endocrine disruptor of the AhR. | Sorafenib | aryl hydrocarbon receptor | Homo sapiens |
| 4 | In summary, we demonstrate that sorafenib is a potent AhR antagonist and likely endocrine disruptor of the AhR. | Sorafenib | aryl hydrocarbon receptor | Homo sapiens |
| 5 | Moreover, sorafenib offers potential benefit for diseases treatable through AhR suppression strategies. | Sorafenib | aryl hydrocarbon receptor | Homo sapiens |
| 6 | Further investigation is warranted into sorafenib"s AhR antagonistic behavior. | Sorafenib | aryl hydrocarbon receptor | Homo sapiens |