Title : A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.

Pub. Date : 2022 Feb 2

PMID : 35110538






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Once in cells, AT-527 is converted into its triphosphate form, AT-9010, that presumably targets the viral RNA-dependent RNA polymerase (RdRp, nsp12), for incorporation into viral RNA. triphosphoric acid ORF1a polyprotein;ORF1ab polyprotein Severe acute respiratory syndrome coronavirus 2