Title : Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN.

Pub. Date : 2022 Feb 7

PMID : 34935867






2 Functional Relationships(s)
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1 Here, we demonstrate that paclitaxel triggers Sarm1-dependent cADPR production in distal axons, promoting intra-axonal calcium flux from both intracellular and extracellular calcium stores. Calcium sterile alpha and TIR motif containing 1 Homo sapiens
2 Here, we demonstrate that paclitaxel triggers Sarm1-dependent cADPR production in distal axons, promoting intra-axonal calcium flux from both intracellular and extracellular calcium stores. Calcium sterile alpha and TIR motif containing 1 Homo sapiens