Pub. Date : 1986 Oct 30
PMID : 3490850
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hyaluronic acid is an endogenous inducer of interleukin-1 production by human monocytes and rabbit macrophages. | Hyaluronic Acid | interleukin 1 alpha | Homo sapiens |
| 2 | When human peripheral monocytes and rabbit peritoneal macrophages were incubated with hyaluronic acid, the media were found to contain interleukin-1 (IL-1) activity and to stimulate collagenase production by rabbit fibroblasts. | Hyaluronic Acid | interleukin 1 alpha | Homo sapiens |
| 3 | When human peripheral monocytes and rabbit peritoneal macrophages were incubated with hyaluronic acid, the media were found to contain interleukin-1 (IL-1) activity and to stimulate collagenase production by rabbit fibroblasts. | Hyaluronic Acid | interleukin 1 alpha | Homo sapiens |
| 4 | A digestion of hyaluronic acid by testicular hyaluronidase decreased the IL-1 inducing activity. | Hyaluronic Acid | interleukin 1 alpha | Homo sapiens |
| 5 | Hyaluronic acid also stimulated human polymorphonuclear leucocytes to produce IL-1 like activity. | Hyaluronic Acid | interleukin 1 alpha | Homo sapiens |
| 6 | These results indicate that hyaluronic acid is an endogenous IL-1 inducer and may play important roles in the pathological and/or physiological changes of connective tissues. | Hyaluronic Acid | interleukin 1 alpha | Homo sapiens |