Title : Characterization of inflammatory mediator release from purified human lung mast cells.

Pub. Date : 1986 Apr

PMID : 3485946






1 Functional Relationships(s)
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1 The optimal concentration of anti-IgE for the release of the arachidonate cyclooxygenase metabolites PGD2 and TxB2 (0.3 microgram/ml) was 10- to 30-fold less than that required for the release of histamine and LTC4 (3 to 10 micrograms/ml), suggesting that these release processes may have differential IgE Fc receptor cross-linking requirements. Histamine prostaglandin D2 synthase Homo sapiens