PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3485946-4 1986 The optimal concentration of anti-IgE for the release of the arachidonate cyclooxygenase metabolites PGD2 and TxB2 (0.3 microgram/ml) was 10- to 30-fold less than that required for the release of histamine and LTC4 (3 to 10 micrograms/ml), suggesting that these release processes may have differential IgE Fc receptor cross-linking requirements. Histamine 196-205 prostaglandin D2 synthase Homo sapiens 101-105