Pub. Date : 2022 Feb
PMID : 34781065
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we found that AHR and IDO1 expression levels were lower in endometriosis PBMCs; however, TCDD treatment increased AHR, FOXP3, IDO1, IL-6, and Treg levels in the endometriosis group (P <= 0.05-0.0001). | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 2 | Here, we found that AHR and IDO1 expression levels were lower in endometriosis PBMCs; however, TCDD treatment increased AHR, FOXP3, IDO1, IL-6, and Treg levels in the endometriosis group (P <= 0.05-0.0001). | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 3 | In conclusion, these results shed light on the probable mechanisms, through which AHR activation by chemical toxicants can impact inflammatory immune mediators involved in the development of endometriosis; also, these data support the idea that TCDD could promote endometriosis progression. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |